of Buah Merah
speculate that Papuan people have been utilizing Buah Merah as
the best source of fruit oil and micro-nutrients such as
carotenoids and vitamin E until the present time for at least
30,000 years since they immigrated at the highlands of Papua,
though they do not know what functional and active ingredients
in Buah Merah are.
can be said that their long time history and experiences of
dietary use of Buah Merah can prove it very safe.
addition to empirical reports, we investigated its safety as
well as cooking and eating procedures on site in Baliem valley.
Each family plants several Buah Merah trees at the garden and/or
vicinity of house and collect one ripen reddish fruit and cook
and make Buah Merah Pasta as mentioned in the above.
Buah Merah trees have never been sprayed with pesticides and
given synthetic fertilizers, but cultivated in purely natural
way. One fruit was enough to serve for more than 10 persons’
Roughly computing, the individuals intake 10~20 g at one time in
Buah Merah oil basis, as about 200 g of Buah Merah oil is
collected from one fruit.
The Pasta is a mixture of cellular matrix including entire fruit
The fibrous layer underlying the flesh was penetrated with Buah
Merah oil and the people took even this part.
We heard that nobody experienced carotenodermia and any other
are no reports on significantly higher-rated or abnormal adverse
events associated with Buah Merah, according to Papuan native
people and health authorities so far we investigated.
Merah oil is extracted from cellular matrix of Buah Merah fruit.
Acute and sub-acute toxicity studies of Buah Merah oil were
conducted using Sprague Dawley rats by oral administration
according to OECD guidelines by M&K Laboratories Inc.
toxicity was not found at 2 ml/kg bodyweight of Buah Merah oil.
In the sub-acute test, 0.1, 0.3 and 1 mL/kg bodyweight of the
test substance were given to the rats for 28 days, but no
untoward findings caused by the test substance were reported
The mutagenicity study of Buah Merah oil disclosed no
mutagenicity in base-pair substitution and frameshift types
is noticed that Buah Merah oil has been produced by paying most
attention to hygiene, by considering the principles of
international standards at the near site of Buah Merah
cultivation areas, Wamena of Baliem valley. According to
internal data of M&K Laboratories Inc., no pathogenic
microorganisms are contaminated in Buah Merah oil.
production method with possible modifications was applied for
approval for patent by M&K Laboratories and CABI to Japan
Patent Office in 2012.
for Agro-Based Industry), Bogor
Ministry of Industry, Indonesia
to above-mentioned nutritional data, pro-vitamin A carotenoids
are concerned in safety issues.
Linus Pauling Institute, Oregon State University in USA
well-summarizes the safety of carotenoids (12), showing that
high dose of beta-carotene (up to 180 mg/day) have been used to
treat erythropoietic protoporphyria without toxic side effects.
30 mg/day or more of beta-carotene supplements and the
consumption of large amount of carotene-rich foods have resulted
in a yellow discoloration of the skin (carotenodermia).
The risks of high-dose beta-carotene supplementation (20~30
mg/day) outweigh any potential benefits for chronic disease
prevention, especially in smokers or other high-risk
There is no reason to limit the consumption of carotenoid-rich
fruits and vegetables during pregnancy.
Pregnant and breast-feeding women should avoid consuming more
than 3 mg/day of beta-carotene from supplements.
of Indonesia and Bandung Institute of Technology, Indonesia
promise that Buah Merah oil dosage of 3 x 1 tablespoon per day
(15 mL x 3 = 45 mL/day) is safe (12).
of beta-cryptoxanthin has not been established, so far we
examined. Beta-cryptoxanthin is naturally contained at contents
of 3.6 mg and 0.4 mg per 1 cup (200 mL) in cooked pumpkin and
fresh orange juice, respectively (12).
Merah oil is comparable with natural fruit and its analysis
results reveal that the contents of beta-carotene and beta-cryptoxanthin
are about 5 mg/100g (0.05 mg/g) each (13).
One (1) mL/kg of rat bodyweight/day (60 mL or 54 g/60 kg human
bodyweight) in 28 days consecutive administration does not show
any toxic side effects (10).
Preliminary pharmacokinetic study of Buah Merah capsule form of
oil showed that beta-carotene and beta-cryptoxanthin were
relatively rapidly absorbed into blood of human subjects (14).
Buah Merah Pasta
with Buah Merah source
Merah sold at public market
these facts and history of use of Buah Merah by Papuan people,
we can conclude that Buah Merah oil is very safe and the dose of
10 g/day may not cause any side-effects in human.
order to maintain health conditions and intake micronutrients,
especially beta-cryptoxanthin from Buah Merah oil, it is
recommended to receive 2 g/day in healthy persons, because
average daily intake of beta-cryptoxanthin in American
population is reported as 104 μg/day (15).
Merah 500VE is typical Buah Merah oil capsule product launched
of now, Buah Merah 500 /500VE capsule products have not been
in any other country except Japan.
We are willing to send Buah Merah 500VE on request of
readers from any country.
It is said that you can purchase food supplements for your self
consumption without permission of authority.
Get Buah Merah 500VE in Japan
of Buah Merah 500VE are
ready to send you by EMS.
The price including EMS charge is USD 180.
Remittance cost is considered to be minimal.
Merah 500VE is
fanatic smokers, patients with cancers, DM, post-menopausal
acne, boldness, malnutrition and other serious diseases,
and for enhance of your health, longevity.
Please contact, Dr. M. Nishigaki,